Use of Inhaled Volatile Anesthetics for Longer Term Critical Care Sedation: A Pilot Randomized Controlled Trial
Angela Jerath, MD, BSc, MSc, FRCPC, FANZCA; Kelvin Wong, MD; Marcin Wasowicz, MD, PhD; Tara Fowler, RRT; Andrew Steel, MD, FRCPC; Deep Grewal, MD; Ella Huszti, PhD; Matteo Parotto, MD, PhD; Haibo Zhang, MD, PhD; M. Elizabeth Wilcox, MD, FRCPC, PhD; Bernard McDonald, MD, PhD, FRCPC; Christopher Overgaard, MD, FRCPC, MSc; Vivek Rao, MD, FRCSC, PhD; Niall D. Ferguson, MD, FRCPC, MSc. Critical Care Explorations – November 2020
Objectives: Assess feasibility, barriers to recruitment, and safety of volatile-based sedation in longer term sedation patients in North American ICUs with limited or no experience with volatile sedation. Design: Open-label, pilot randomized clinical trial performed between October 2013 and September 2018.